Futibatinib (TAS-120)
Futibatinib (TAS-120) is an irreversible fibroblast growth factor receptor (FGFR) inhibitor which inhibits all 4 subtypes of FGFR with enzyme IC50 values of 1.8 nM, 1.4 nM, 1.6 nM and 3.7 nM for FGFR1, FGFR2, FGFR3 and FGFR4, respectively.
Trivial name | N/A |
Catalog Number | S8848 |
Molecular Formula | C22H22N6O3 |
CAS# | 1448169-71-8 |
Inchi | InChI=1S/C22H22N6O3/c1-4-19(29)27-8-7-15(12-27)28-22-20(21(23)24-13-25-22)18(26-28)6-5-14-9-16(30-2)11-17(10-14)31-3/h4,9-11,13,15H,1,7-8,12H2,2-3H3,(H2,23,24,25) |
Inchi Key | KEIPNCCJPRMIAX-UHFFFAOYSA-N |
SMILES | COC1=CC(=CC(=C1)C#CC2=NN(C3=NC=NC(=C23)N)C4CCN(C4)C(=O)C=C)OC |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/tas-120.html |
Additional Information | https://file.selleck.cn/downloads/struct/tas-120-chemical-structure-s8848.gif |