Y-29794 tosylate | MedChemExpress (MCE)
Y-29794 tosylate is a selective, orally active inhibitor for non-peptide prolyl endopeptidase (PPCE), with an IC50 of 3 nM and a Ki of 0.95 nM. Y-29794 tosylate enhances the effect of thyrotropin-releasing hormone (TRH) on the release of ACh in the rat hippocampus, exhibits potential neuroprotective efficacy. Y-29794 tosylate exhibits anticancer activity through inhibition of the IRS1-AKT-mTORC1 pathway. Y-29794 tosylate penetrates the brain-blood barrier (BBB)[1][2].
| Trivial name | Y-29794 tosylate |
| Catalog Number | HY-15113A |
| Research Area | Neurological Disease; Cancer |
| CAS# | 143984-17-2 |
| Purity | ≥98.0% |
| SMILES | O=C(C1=CC=C(C(C)C)N=C1SCCCCCCCCN(C)C)C2=CC=CS2.O=S(C3=CC=C(C)C=C3)(O)=O |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/y-29794-tosylate.html |