LDN-193189 dihydrochloride | MedChemExpress (MCE)
LDN-193189 (dihydrochloride) is a potent selective BMP type I receptor (BMP I) inhibitor. LDN-193189 efficiently inhibits transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50 values of 5 nM and 30 nM, respectively. LDN-193189 can be used for the research of bone morphogenetic protein signalling, such as fibrodysplasia ossificans progressiva[1][2][3].
| Trivial name | LDN-193189 dihydrochloride |
| Catalog Number | HY-12071B |
| Alternative Name(s) | DM-3189 dihydrochloride |
| Research Area | Cancer |
| CAS# | 1435934-00-1 |
| Purity | 99.75% |
| SMILES | C1(C2=C3N=CC(C4=CC=C(N5CCNCC5)C=C4)=CN3N=C2)=CC=NC6=CC=CC=C16.Cl.Cl |
| PubChem Chemical Structure ID | 91900717 |
| Size | 50 mg |
| Supplier Page | https://www.medchemexpress.com/ldn-193189-dihydrochloride.html |