LDN-212854
LDN-212854 (BMP Inhibitor III) is a potent and selective BMP receptor inhibitor withIC50 of 1.3 nM for ALK2, about 2-, 66-, 1641-, and 7135-fold selectivity over ALK1, ALK3, ALK4, and ALK5, respectively.
Trivial name | BMP Inhibitor III |
Catalog Number | S7147 |
Molecular Formula | C25 H22 N6 |
CAS# | 1432597-26-6 |
Inchi | InChI=1S/C25H22N6/c1-3-21(22-4-2-10-27-24(22)5-1)23-16-29-31-17-19(15-28-25(23)31)18-6-8-20(9-7-18)30-13-11-26-12-14-30/h1-10,15-17,26H,11-14H2 |
Inchi Key | BBDGBGOVJPEFBT-UHFFFAOYSA-N |
SMILES | C1CN(CCN1)C2=CC=C(C=C2)C3=CN4C(=C(C=N4)C5=C6C=CC=NC6=CC=C5)N=C3 |
Size | 10mg |
Supplier Page | http://www.selleckchem.com/products/ldn-212854.html |
Additional Information | https://file.selleck.cn/downloads/struct/LDN-212854-chemical-structure-s7147.gif |