Lopinavir-d7 | MedChemExpress (MCE)
Lopinavir-d7 is deuterated labeled Lopinavir (HY-14588). Lopinavir (ABT-378) is a highly potent, selective peptidomimetic inhibitor of the HIV-1 protease, with Kis of 1.3 to 3.6 pM for wild-type and mutant HIV protease. Lopinavir acts by arresting maturation of HIV-1 thereby blocking its infectivity[1][2]. Lopinavir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 14.2 μM[3].
| Trivial name | Lopinavir-d7 |
| Catalog Number | HY-14588S2 |
| Alternative Name(s) | ABT-378-d7 |
| Research Area | Infection; Cancer |
| CAS# | 1432060-78-0 |
| Purity | ≥98.0% |
| SMILES | CC1=C(OCC(N[C@@H](CC2=CC=CC=C2)[C@@H](O)C[C@H](CC3=CC=CC=C3)NC([C@H](C([2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])N4C(NCCC4)=O)=O)=O)C(C)=CC=C1 |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/lopinavir-d7.html |