CCT241533 hydrochloride
CCT241533 hydrochloride is an ATP competitive, potent, and selective inhibitor of CHK2 with an IC50 of 3 nM and a Ki of 1.16 nM and shows minimal cross-reactivity against a panel of kinases. CCT241533 inhibits CHK2 activity in human tumor cell lines when subjected to DNA damage.
Catalog Number | E1653 |
Molecular Formula | C21H31N5O2 |
CAS# | 1431697-96-9 |
SMILES | C1CC(CCO1)C2=C[NH]C3=NC=NC(=C23)NC4CCC(CC4)N5CCOCC5 |
Size | 1mg |
Supplier Page | http://www.selleckchem.com/products/cct241533-hydrochloride.html |
Additional Information | https://file.selleck.cn/downloads/struct/e1653-CCT241533-hydrochloride-chemical-structure.png |