A-1331852
A-1331852 is a potent and selectiveBCL-XL inhibitor with Ki value less than 0.01 nM for BCL-XL and 6 nM, 4 nM, 142 nM for Bcl-2, Bcl-W, MCL-1 respectively. It may be useful in the treatment of cancer, immune and autoimmune diseases.
| Trivial name | N/A |
| Catalog Number | S7801 |
| Molecular Formula | C38H38N6O3S |
| CAS# | 1430844-80-6 |
| Inchi | InChI=1S/C38H38N6O3S/c1-22-29(19-39-44(22)21-38-16-23-13-24(17-38)15-25(14-23)18-38)27-9-10-33(41-34(27)36(46)47)43-12-11-26-5-4-6-28(30(26)20-43)35(45)42-37-40-31-7-2-3-8-32(31)48-37/h2-10,19,23-25H, 11-18,20-21H2,1H3,(H,46,47)(H,40,42,45) |
| Inchi Key | QCQQONWEDCOTBV-UHFFFAOYSA-N |
| SMILES | CC1=C(C=NN1CC23CC4CC(C2)CC(C4)C3)C5=C(N=C(C=C5)N6CCC7=C(C6)C(=CC=C7)C(=O)NC8=NC9=CC=CC=C9S8)C(=O)O |
| Size | 100mg |
| Supplier Page | http://www.selleckchem.com/products/a-1331852.html |
| Additional Information | https://file.selleck.cn/downloads/struct/a-1331852-chemical-structure-s7801.gif |