IDF-11774
IDF-11774 is a hypoxia-inducible factor-1 (HIF-1) inhibitor. It reduces the HRE-luciferase activity of HIF-1α (IC50 = 3.65 μM) and blocks HIF-1α accumulation under hypoxia in HCT116 human colon cancer cells.
| Trivial name | N/A |
| Catalog Number | S8771 |
| Molecular Formula | C23H32N2O2 |
| CAS# | 1429054-28-3 |
| Inchi | InChI=1S/C23H32N2O2/c1-24-6-8-25(9-7-24)22(26)16-27-21-4-2-20(3-5-21)23-13-17-10-18(14-23)12-19(11-17)15-23/h2-5,17-19H,6-16H2,1H3 |
| Inchi Key | QGBBBLPWBSWERZ-UHFFFAOYSA-N |
| SMILES | CN1CCN(CC1)C(=O)COC2=CC=C(C=C2)C34CC5CC(C3)CC(C5)C4 |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/idf-11774.html |
| Additional Information | https://file.selleck.cn/downloads/struct/idf-11774-chemical-structure-s8771.gif |