Zanapezil | MedChemExpress (MCE)
Zanapezil (TAK-147) is a potent, reversible and selective acetylcholine esterase (AChE) inhibitor. Zanapezil shows a potent and reversible inhibition of AChE activity in homogenates of the rat cerebral cortex (IC50=51.2 nM). Zanapezil shows a moderate inhibition of muscarinic M1 and M2 receptor binding with Ki values of 234 and 340 nM, respectively. Zanapezil can be used for the research of early stages of Alzheimer’s disease (AD)[1][2].
| Trivial name | Zanapezil |
| Catalog Number | HY-19651A |
| Alternative Name(s) | TAK-147 |
| Research Area | Neurological Disease |
| CAS# | 142852-51-5 |
| Purity | ≥98.0% |
| SMILES | O=C(C1=CC=C2CCCCNC2=C1)CCC3CCN(CC4=CC=CC=C4)CC3.O=C(O)/C=C/C(O)=O |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/zanapezil.html |