Adefovir Dipivoxil
Adefovir Dipivoxil is a acyclic nucleotide analog reverse transcriptase inhibitor (ntRTI). It is phosphorylated to the active metabolite adefovir diphosphate by cellular kinases. Adefovir diphosphate inhibits HBV DNA polymerase (reverse transcriptase) by competing with the natural substrate deoxyadenosine triphosphate and by causing DNA chain termination after its incorporation into viral DNA.
| Catalog Number | 10-101-107 |
| Alternative Name(s) | Adefovir di(pivaloyloxymethyl) ester,Bis(POM)PMEA, GS-0840, Piv2PMEA,9-[2-(Bis[(pivaloyloxy)-methoxy]phosphinylmethoxy)ethyl]adenine |
| Research Area | For treatment of hepatitis B and herpes simplex virus infection |
| Molecular Formula | C20H32N5O8P |
| CAS# | 142340-99-6 |
| Purity | >98% |
| Inchi | InChI=1S/C20H32N5O8P/c1-19(2,3)17(26)30-11-32-34(28,33-12-31-18(27)20(4,5)6)13-29-8-7-25-10-24-14-15(21)22-9-23-16(14)25/h9-10H,7-8,11-13H2,1-6H3,(H2,21,22,23) |
| Inchi Key | WOZSCQDILHKSGG-UHFFFAOYSA-N |
| Size | Inquiry |
| Supplier Page | https://www.creative-peptides.com/product/adefovir-dipivoxil-item-10-101-107-4.html |