Crenigacestat (LY3039478)
Crenigacestat (LY3039478) is an oral Notch and gamma-secretase inhibitor with IC50 of 0.41 nM for Notch.
| Catalog Number | S7169 |
| Molecular Formula | C22H23F3N4O4 |
| CAS# | 1421438-81-4 |
| Inchi | InChI=1S/C22H23F3N4O4/c1-13(27-17(31)8-9-22(23,24)25)20(32)28-18-15-6-3-2-5-14(15)16-7-4-10-26-19(16)29(11-12-30)21(18)33/h2-7,10,13,18,30H,8-9,11-12H2,1H3,(H,27,31)(H,28,32)/t13-,18-/m0/s1 |
| Inchi Key | YCBAQKQAINQRFW-UGSOOPFHSA-N |
| SMILES | CC(C(=O)NC1C2=CC=CC=C2C3=C(N=CC=C3)N(C1=O)CCO)NC(=O)CCC(F)(F)F |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/ly3039478.html |
| Additional Information | https://file.selleck.cn/downloads/struct/LY3039478-chemical-structure-s7169.gif |