Bioymifi
Bioymifi, a small-molecule death receptor 5 (DR5) agonist, binds to the extracellular domain(ECD) of DR5 with a Kd of 1.2 μM but showed little binding affinity to the DR4 ECD. It induces DR5 clustering and aggregation, leading to apoptosis.
| Trivial name | N/A |
| Catalog Number | S7942 |
| Molecular Formula | C22H12BrN3O4S |
| CAS# | 1420071-30-2 |
| Inchi | InChI=1S/C22H12BrN3O4S/c23-12-2-4-13(5-3-12)26-21(29)18(31-22(26)24)10-14-6-8-17(30-14)11-1-7-15-16(9-11)20(28)25-19(15)27/h1-10,24H,(H,25,27,28)/b18-10-,24-22? |
| Inchi Key | ULBOWKXOFOTCMU-NLDKGBHCSA-N |
| SMILES | C1=CC(=CC=C1N2C(=O)C(=CC3=CC=C(O3)C4=CC5=C(C=C4)C(=O)NC5=O)SC2=N)Br |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/bioymifi.html |
| Additional Information | https://file.selleck.cn/downloads/struct/bioymifi-chemical-structure-S7942.gif |