Cu-CPT22
CU-CPT22 shows dose-dependent inhibitory effects blocking Pam3CSK4-induced TLR1/2 activation with an IC50 of 0.58 ± 0.09 µM while no significant inhibition to TLR2/6. It demonstrates minimal non-specific inhibition against a panel of 10 representative kinases (PDGFRB, MET, DDR2, SRC, MAPK1, PAK1, AKT1, PKC-γ, CAMK1, and PLK4).
| Trivial name | N/A |
| Catalog Number | S8677 |
| Molecular Formula | C19H22O7 |
| CAS# | 1416324-85-0 |
| Inchi | InChI=1S/C19H22O7/c1-3-4-5-6-7-26-19(24)12-8-11-10-14(25-2)17(22)18(23)15(11)16(21)13(20)9-12/h8-10,22-23H,3-7H2,1-2H3,(H,20,21) |
| Inchi Key | UBQFTTUFRSSOHE-UHFFFAOYSA-N |
| SMILES | CCCCCCOC(=O)C1=CC2=C(C(=C(O)C(=C2)OC)O)C(=O)C(=C1)O |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/cu-cpt22.html |
| Additional Information | https://file.selleck.cn/downloads/struct/cu-cpt22-chemical-structure-s8677.gif |