TG6-10-1
TG6-10-1 is a selective, brain-penetrant antagonist of EP2 receptor with nanomolar potency. It reduces delayed mortality, neuroinflammation, and hippocampal neurodegeneration after status epilepticus (SE) in mice. TG6-10-1 provides neuroprotection via anti-inflammatory mechanisms without direct anticonvulsant effects.
| Catalog Number | E8198 |
| Molecular Formula | C25H22O10 |
| CAS# | 1415716-58-3 |
| Inchi | InChI=1S/C25H22O10/c1-32-17-6-11(2-4-14(17)28)24-20(10-26)33-16-5-3-12(7-18(16)34-24)25-23(31)22(30)21-15(29)8-13(27)9-19(21)35-25/h2-9,20,23-29,31H,10H2,1H3/t20-,23+,24-,25-/m1/s1 |
| Inchi Key | SEBFKMXJBCUCAI-HKTJVKLFSA-N |
| SMILES | COC1=C(C=CC(=C1)C2C(OC3=C(O2)C=C(C=C3)C4C(C(=O)C5=C(C=C(C=C5O4)O)O)O)CO)O |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/tg6-10-1.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E8198-TG6-10-1-chemical-structure.png |