PF-543 hydrochloride
PF-543 hydrochloride, a novel sphingosine-competitive inhibitor of SphK1, inhibits SphK1 with IC50 and Ki of 2.0 nM and 3.6 nM, exhibits >100-fold selectivity over the SphK2 isoform. PF-543 hydrochloride induces apoptosis, necrosis, and autophagy.
| Trivial name | N/A |
| Catalog Number | S7177 |
| CAS# | 1706522-79-3 |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/pf-543.html |
| Additional Information | https://file.selleck.cn/downloads/struct/PF-543-chemical-structure-s7177.gif |