PF-543 hydrochloride

PF-543 hydrochloride, a novel sphingosine-competitive inhibitor of SphK1, inhibits SphK1 with IC50 and Ki of 2.0 nM and 3.6 nM, exhibits >100-fold selectivity over the SphK2 isoform. PF-543 hydrochloride induces apoptosis, necrosis, and autophagy.

Price Not Available 5mg PF-543 hydrochloride Supplier Page

Trivial name	N/A
Catalog Number	S7177
Molecular Formula	C27H32ClNO4S
CAS#	1706522-79-3
Inchi	InChI=1S/C27H31NO4S/c1-21-14-24(20-33(30,31)27-7-3-2-4-8-27)16-26(15-21)32-19-23-11-9-22(10-12-23)17-28-13-5-6-25(28)18-29/h2-4,7-12,14-16,25,29H,5-6,13,17-20H2,1H3/t25-/m1/s1
Inchi Key	NPUXORBZRBIOMQ-RUZDIDTESA-N
SMILES	CC1=CC(=CC(=C1)OCC2=CC=C(C=C2)CN3CCCC3CO)CS(=O)(=O)C4=CC=CC=C4.Cl
Size	5mg
Supplier Page	http://www.selleckchem.com/products/pf-543.html
Additional Information	https://file.selleck.cn/downloads/struct/PF-543-chemical-structure-s7177.gif