ABT-751 (E7010)

ABT-751 (E7010) binds to the colchicine site on β-tubulin and inhibits polymerization of microtubules, not a substrate for the MDR transporter and is active against cell lines resistant to vincristine, doxorubicin, and cisplatin. Phase 1/2.

Price Not Available 10mM/1mL ABT-751 (E7010) Supplier Page
Trivial name N/A
Catalog Number S1165
Molecular Formula C15H13I2NO4
CAS# 141430-65-1
Inchi InChI=1S/C15H13I2NO4/c16-11-5-8(7-13(18)15(20)21)6-12(17)14(11)22-10-3-1-9(19)2-4-10/h1-6,13,19H,7,18H2,(H,20,21)/t13-/m0/s1
Inchi Key ZHSOTLOTTDYIIK-ZDUSSCGKSA-N
SMILES C1=CC(=CC=C1O)OC2=C(C=C(C=C2I)CC(C(=O)O)N)I
Size 10mM/1mL
Supplier Page http://www.selleckchem.com/products/ABT-751.html
Additional Information https://file.selleck.cn/downloads/struct/ABT-751-chemical-structure-S1165.gif