ABT-751 (E7010)
ABT-751 (E7010) binds to the colchicine site on β-tubulin and inhibits polymerization of microtubules, not a substrate for the MDR transporter and is active against cell lines resistant to vincristine, doxorubicin, and cisplatin. Phase 1/2.
Trivial name | N/A |
Catalog Number | S1165 |
Molecular Formula | C15H13I2NO4 |
CAS# | 141430-65-1 |
Inchi | InChI=1S/C15H13I2NO4/c16-11-5-8(7-13(18)15(20)21)6-12(17)14(11)22-10-3-1-9(19)2-4-10/h1-6,13,19H,7,18H2,(H,20,21)/t13-/m0/s1 |
Inchi Key | ZHSOTLOTTDYIIK-ZDUSSCGKSA-N |
SMILES | C1=CC(=CC=C1O)OC2=C(C=C(C=C2I)CC(C(=O)O)N)I |
Size | 10mM/1mL |
Supplier Page | http://www.selleckchem.com/products/ABT-751.html |
Additional Information | https://file.selleck.cn/downloads/struct/ABT-751-chemical-structure-S1165.gif |