ABT-751 (E7010)

ABT-751 (E7010) binds to the colchicine site on β-tubulin and inhibits polymerization of microtubules, not a substrate for the MDR transporter and is active against cell lines resistant to vincristine, doxorubicin, and cisplatin. Phase 1/2.

Price Not Available 10mM/1mL ABT-751 (E7010) Supplier Page
Trivial name N/A
Catalog Number S1165
Molecular Formula C18H17N3O4S
CAS# 141430-65-1
Inchi InChI=1S/C18H17N3O4S/c1-25-15-8-10-16(11-9-15)26(23,24)21-17-3-2-12-19-18(17)20-13-4-6-14(22)7-5-13/h2-12,21-22H,1H3,(H,19,20)
Inchi Key URCVCIZFVQDVPM-UHFFFAOYSA-N
SMILES COC1=CC=C(C=C1)S(=O)(=O)NC2=C(N=CC=C2)NC3=CC=C(C=C3)O
Size 10mM/1mL
Supplier Page http://www.selleckchem.com/products/ABT-751.html
Additional Information https://file.selleck.cn/downloads/struct/ABT-751-chemical-structure-S1165.gif