ABT-751 (E7010)
ABT-751 (E7010) binds to the colchicine site on β-tubulin and inhibits polymerization of microtubules, not a substrate for the MDR transporter and is active against cell lines resistant to vincristine, doxorubicin, and cisplatin. Phase 1/2.
| Trivial name | N/A |
| Catalog Number | S1165 |
| Molecular Formula | C18H17N3O4S |
| CAS# | 141430-65-1 |
| Inchi | InChI=1S/C18H17N3O4S/c1-25-15-8-10-16(11-9-15)26(23,24)21-17-3-2-12-19-18(17)20-13-4-6-14(22)7-5-13/h2-12,21-22H,1H3,(H,19,20) |
| Inchi Key | URCVCIZFVQDVPM-UHFFFAOYSA-N |
| SMILES | COC1=CC=C(C=C1)S(=O)(=O)NC2=C(N=CC=C2)NC3=CC=C(C=C3)O |
| Size | 10mg |
| Supplier Page | http://www.selleckchem.com/products/ABT-751.html |
| Additional Information | https://file.selleck.cn/downloads/struct/ABT-751-chemical-structure-S1165.gif |