EVT801
EVT801 is a potent and selective inhibitor of VEGFR-3 with an IC50 of 11 nM. It exhibits potent antitumor effects and represents a promising anti-lymphangiogenic drug in patients with VEGFR-3 positive tumors.
| Catalog Number | E4694 |
| Molecular Formula | C42H45ClN6O5S2 |
| CAS# | 1412453-70-3 |
| Inchi | InChI=1S/C42H45ClN6O5S2/c1-46(2)23-22-35(30-55-37-9-4-3-5-10-37)44-40-21-20-38(28-41(40)49(51)52)56(53,54)45-42(50)32-14-18-36(19-15-32)48-26-24-47(25-27-48)29-33-8-6-7-11-39(33)31-12-16-34(43)17-13-3 1/h3-21,28,35,44H,22-27,29-30H2,1-2H3,(H,45,50)/t35-/m1/s1 |
| Inchi Key | HPLNQCPCUACXLM-PGUFJCEWSA-N |
| SMILES | CN(C)CCC(CSC1=CC=CC=C1)NC2=C(C=C(C=C2)S(=O)(=O)NC(=O)C3=CC=C(C=C3)N4CCN(CC4)CC5=CC=CC=C5C6=CC=C(C=C6)Cl)[N+](=O)[O-] |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/evt801.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E4694-EVT801-chemical-structure.png |