JNK-IN-8
JNK-IN-8 (JNK Inhibitor XVI) is the first irreversible JNK inhibitor for JNK1, JNK2 and JNK3 with IC50 of 4.7 nM, 18.7 nM and 1 nM, >10-fold selectivity against MNK2, Fms and no inhibition to c-Kit, Met, PDGFRβin A375 cell line.
| Trivial name | JNK Inhibitor XVI |
| Catalog Number | S4901 |
| Molecular Formula | C19H23Cl2N3O4 |
| CAS# | 1410880-22-6 |
| SMILES | CC(C)CC(C(=O)O)NC(CC1=CN=CN1CC2=CC(=CC(=C2)Cl)Cl)C(=O)O |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/jnk-in-8.html |
| Additional Information | https://file.selleck.cn/downloads/struct/JNK-IN-8-chemical-structure-s4901.gif |