(+)-ITD-1
(+)-ITD-1 is the (+)-enantiomer of ITD 1 that is more active. ITD-1 is a selective inhibitor of TGFβ/Smad signaling (IC50 values 0.46 μM and 6.90 μM for (+)-ITD 1 and (−)-ITD 1, respectively for TGF-β inhibition) that clears the type II TGFβ receptor from the cell surface. ITD 1 promotes the differentiation of cardiomyocytes and cardiogenesis in murine embryonic stem cell (mESCs).
Catalog Number | 1409968-46-2 |
CAS# | 1409968-46-2 |
Purity | 99% |
Size | Please inquire |
Supplier Page | https://www.bocsci.com/itd-1-cas-1409968-46-2-item-55370.html |