(+)-ITD-1

(+)-ITD-1 is the (+)-enantiomer of ITD 1 that is more active. ITD-1 is a selective inhibitor of TGFβ/Smad signaling (IC50 values 0.46 μM and 6.90 μM for (+)-ITD 1 and (−)-ITD 1, respectively for TGF-β inhibition) that clears the type II TGFβ receptor from the cell surface. ITD 1 promotes the differentiation of cardiomyocytes and cardiogenesis in murine embryonic stem cell (mESCs).

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Catalog Number 1409968-46-2
CAS# 1409968-46-2
Purity 99%
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Supplier Page https://www.bocsci.com/itd-1-cas-1409968-46-2-item-55370.html