PFI-1 (PF-6405761)
PFI-1 (PF-6405761) is a highly selective BET (bromodomain-containing protein) inhibitor for BRD4 with IC50 of 0.22 μM and for BRD2 with IC50 of 98 nM in a cell-free assay.
| Trivial name | N/A |
| Catalog Number | S1216 |
| Molecular Formula | C19H20N4O3 |
| CAS# | 1403764-72-6 |
| Inchi | InChI=1S/C19H20N4O3/c1-20-19(24)11-22-18-10-21-14-6-4-12(8-15(14)23-18)13-5-7-16(25-2)17(9-13)26-3/h4-10H,11H2,1-3H3,(H,20,24)(H,22,23) |
| Inchi Key | LYPCULYCGFOIDA-UHFFFAOYSA-N |
| SMILES | CNC(=O)CNC1=CN=C2C=CC(=CC2=N1)C3=CC(=C(C=C3)OC)OC |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/pfl-1.html |
| Additional Information | https://file.selleck.cn/downloads/struct/PF-06405761-chemical-structure-s1216.gif |
