Dihexa | MedChemExpress (MCE)
Dihexa, an oligopeptide drug, is an orally active and blood-brain barrier-permeable angiotensin IV analog. Dihexa binds to hepatocyte growth factor (HGF) with high affinity (Kd=65 pM) and potentiates its activity at its receptor, c-Met. Dihexa exhibits excellent antidementia activity and improves cognitive function in animal models. Dihexa may have therapeutic potential as a treatment Alzheimer’s disease[1][2].
| Trivial name | Dihexa |
| Catalog Number | HY-16969 |
| Alternative Name(s) | PNB-0408; N-hexanoic-Try-Ile-(6)-amino hexanoic amide; Hexanoyl-Tyr-Ile-Ahx-NH2 |
| CAS# | 1401708-83-5 |
| Purity | 99.2% |
| SMILES | OC(C=C1)=CC=C1C[C@H](NC(CCCCC)=O)C(N[C@@H]([C@@H](C)CC)C(NCCCCCC(N)=O)=O)=O |
| Size | 10 mM * 1 mL |
| Supplier Page | https://www.medchemexpress.com/Dihexa.html |