EPZ005687
EPZ005687 is a potent and selective inhibitor of EZH2 with Ki of 24 nM in a cell-free assay, 50-fold selectivity against EZH1 and 500-fold selectivity against 15 other protein methyltransferases.
| Trivial name | N/A |
| Catalog Number | S7004 |
| Molecular Formula | C32H37N5O3 |
| CAS# | 1396772-26-1 |
| Inchi | InChI=1S/C32H37N5O3/c1-21-15-22(2)35-32(39)28(21)18-33-31(38)27-16-25(17-30-29(27)19-34-37(30)26-5-3-4-6-26)24-9-7-23(8-10-24)20-36-11-13-40-14-12-36/h7-10,15-17,19,26H,3-6,11-14,18,20H2,1-2H3,(H,33,3 8)(H,35,39) |
| Inchi Key | ZOIBZSZLMJDVDQ-UHFFFAOYSA-N |
| SMILES | CC1=CC(=C(C(=O)N1)CNC(=O)C2=C3C=NN(C3=CC(=C2)C4=CC=C(C=C4)CN5CCOCC5)C6CCCC6)C |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/epz005687.html |
| Additional Information | https://file.selleck.cn/downloads/struct/EPZ005687-chemical-structure-s7004.gif |