VU0463271
VU0463271 is a selective and potent antagonist of neuronal-specific potassium-chloride cotransporter 2 KCC2, with an IC50 of 61 nM. VU0463271 demonstrates over 100-fold selectivity compared to the closely related Na-K-2Cl cotransporter 1 (NKCC1).
Catalog Number | E1632 |
Molecular Formula | C11H9ClN2OS |
CAS# | 1391737-01-1 |
SMILES | ClC1=CC=CC=C1CC(=O)NC2=NC=CS2 |
Size | 100mg |
Supplier Page | http://www.selleckchem.com/products/vu0463271.html |
Additional Information | https://file.selleck.cn/downloads/struct/E1632-VU0463271-chemical-structure.png |