Bisindolylmaleimide IX (Ro 31-8220) Mesylate

Bisindolylmaleimide IX (Ro 31-8220 Mesylate) is a pan-PKC inhibitor with IC50 of 5 nM, 24 nM, 14 nM, 27 nM, and 24 nM for PKC-α, PKC-βI, PKC-βII, PKC-γ, and PKC-ε, respectively, and also shows potent inhibition against MAPKAP-K1b, MSK1, GSK3β and S6K1.

Price Not Available 10mM/1mL Bisindolylmaleimide IX (Ro 31-8220) Mesylate Supplier Page

Catalog Number	S7207
Molecular Formula	C25H23N5O2S.CH4O3S
CAS#	138489-18-6
Inchi	InChI=1S/C25H23N5O2S.CH4O3S/c1-29-13-17(15-7-2-4-9-19(15)29)21-22(24(32)28-23(21)31)18-14-30(11-6-12-33-25(26)27)20-10-5-3-8-16(18)20;1-5(2,3)4/h2-5,7-10,13-14H,6,11-12H2,1H3,(H3,26,27)(H,28,31,32);1H 3,(H,2,3,4)
Inchi Key	SAWVGDJBSPLRRB-UHFFFAOYSA-N
SMILES	CN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=CN(C5=CC=CC=C54)CCCSC(=N)N.CS(=O)(=O)O
Size	10mM/1mL
Supplier Page	http://www.selleckchem.com/products/ro-31-8220-mesylate.html
Additional Information	https://file.selleck.cn/downloads/struct/Ro-31-8220-mesylate-chemical-structure-s7207.gif