NT157
NT157, a selective inhibitor of IRS-1/2(insulin receptor substrate), has the potential to inhibit IGF-1R and STAT3 signaling pathways in cancer cells and stroma cells of TME leading to a decrease in cancer cell survival.
Trivial name | N/A |
Catalog Number | S8228 |
Molecular Formula | C16H14BrNO5S |
CAS# | 1384426-12-3 |
Inchi | InChI=1S/C16H14BrNO5S/c17-10-3-8(4-11(19)15(10)22)1-2-14(24)18-7-9-5-12(20)16(23)13(21)6-9/h1-6,19-23H,7H2,(H,18,24)/b2-1+ |
Inchi Key | NIPUPOUEGOSAAO-OWOJBTEDSA-N |
SMILES | C1=C(C=C(C(=C1O)O)O)CNC(=S)C=CC2=CC(=C(C(=C2)Br)O)O |
Size | 2mg |
Supplier Page | http://www.selleckchem.com/products/nt157.html |
Additional Information | https://file.selleck.cn/downloads/struct/nt157-chemical-structure-s8228.gif |