Lanabecestat (AZD3293)
Lanabecestat (AZD3293, LY3314814) is an oral beta-secretase 1 cleaving enzyme (BACE) inhibitor with an inhibitory constant Ki of 0.4 nM.
Trivial name | LY3314814 |
Catalog Number | S8193 |
Molecular Formula | C26H28N4O |
CAS# | 1383982-64-6 |
Inchi | InChI=1S/C26H28N4O/c1-4-5-18-12-21(16-28-15-18)19-6-7-20-14-25(10-8-22(31-3)9-11-25)26(23(20)13-19)29-17(2)24(27)30-26/h6-7,12-13,15-16,22H,8-11,14H2,1-3H3,(H2,27,30)/t22-,25-,26-/m0/s1 |
Inchi Key | WKDNQONLGXOZRG-HRNNMHKYSA-N |
SMILES | CC#CC1=CC(=CN=C1)C2=CC3=C(CC4(C35N=C(C(=N5)N)C)CCC(CC4)OC)C=C2 |
Size | 2mg |
Supplier Page | http://www.selleckchem.com/products/azd3293-ly3314814.html |
Additional Information | https://file.selleck.cn/downloads/struct/azd3293-ly3314814-chemical-structure-s8193.gif |