Tropifexor (LJN452)

Tropifexor (LJN452) is a novel and highly potent agonist of FXR with EC50 of 0.2 nM in HTRF assay. It shows no significant off-target activity against a broad panel of enzyme, ion channel, nuclear receptor, and GPCR (>10000-fold selectivity for FXR).

Price Not Available 2mg Tropifexor (LJN452) Supplier Page

Trivial name	N/A
Catalog Number	S8733
Molecular Formula	C29H25F4N3O5S
CAS#	1383816-29-2
Inchi	InChI=1S/C29H25F4N3O5S/c30-21-9-15(27(37)38)10-23-25(21)34-28(42-23)36-16-7-8-17(36)12-18(11-16)39-13-20-24(35-41-26(20)14-5-6-14)19-3-1-2-4-22(19)40-29(31,32)33/h1-4,9-10,14,16-18H,5-8,11-13H2,(H,37, 38)/t16-,17+,18+
Inchi Key	VYLOOGHLKSNNEK-PIIMJCKOSA-N
SMILES	C1CC1C2=C(C(=NO2)C3=CC=CC=C3OC(F)(F)F)COC4CC5CCC(C4)N5C6=NC7=C(C=C(C=C7S6)C(=O)O)F
Size	2mg
Supplier Page	http://www.selleckchem.com/products/tropifexor-ljn452.html
Additional Information	https://file.selleck.cn/downloads/struct/tropifexor-ljn52-chemical-structure-s8733.gif