(−)-Viriditoxin

(−)-Viriditoxin is a mycotoxin originally isolated from A. viridinutans. Exhibits broad activity against Gram-positive bacteria. Bacterial cell division protein FtsZ inhibitor (IC50=8.2µg/ml). Inhibits the GTPase activity of FtsZ in vitro (IC50 = 7.0 µg/ml). Induces apoptosis and autophagy and inhibits cell growth at G2/M in human prostate cancer cells. Activates ATP hydrolysis and induces calcium sensitized swelling of rat liver mitochondria.

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Catalog Number 1381782-08-6
Alternative Name(s) UNII-6TAK972FMC; 6TAK972FMC
Molecular Formula C34H30O14
CAS# 1381782-08-6
Purity ≥98%
Inchi InChI=1S/C34H30O14/c1-43-21-11-19(35)27-17(7-13-5-15(9-23(37)45-3)47-33(41)25(13)31(27)39)29(21)30-18-8-14-6-16(10-24(38)46-4)48-34(42)26(14)32(40)28(18)20(36)12-22(30)44-2/h7-8,11-12,15-16,35-36,39-40H,5-6,9-10H2,1-4H3/t15-,16-/m0/s1
Inchi Key GMCZVCXZGZGZPX-HOTGVXAUSA-N
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