Pelabresib (CPI-0610)
Pelabresib (CPI-0610) is a potent and selective benzoisoxazoloazepine BET bromodomain inhibitor with an IC50 of 39 nM for BRD4-BD1 in TR-FRET assay and currently undergoing human clinical trials for hematological malignancies. CPI-0610 inhibits the expression of Nuclear receptor binding SET domain protein 3 (NSD3) target genes.
| Trivial name | N/A |
| Catalog Number | S7853 |
| Molecular Formula | C20H16ClN3O2 |
| CAS# | 1380087-89-7 |
| SMILES | CC1=NOC2=C1C3=CC=CC=C3C(=NC2CC(=O)N)C4=CC=C(C=C4)Cl |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/cpi-0610.html |
| Additional Information | https://file.selleck.cn/downloads/struct/cpi-0610-chemical-structure-s7853.gif |