CNX-2006
CNX-2006 is a novel irreversible mutant-selective EGFR inhibitor with IC50 of < 20 nM, with very weak inhibition at wild-type EGFR.
Trivial name | N/A |
Catalog Number | S7206 |
Molecular Formula | C26H27F4N7O2 |
CAS# | 1375465-09-0 |
Inchi | InChI=1S/C26H27F4N7O2/c1-3-23(38)33-16-5-4-6-17(11-16)34-24-20(26(28,29)30)13-31-25(36-24)35-21-8-7-18(12-22(21)39-2)32-19-14-37(15-19)10-9-27/h3-8,11-13,19,32H,1,9-10,14-15H2,2H3,(H,33,38)(H2,31,34,3 5,36) |
Inchi Key | BFSRTTWIPACGMI-UHFFFAOYSA-N |
SMILES | COC1=C(C=CC(=C1)NC2CN(C2)CCF)NC3=NC=C(C(=N3)NC4=CC(=CC=C4)NC(=O)C=C)C(F)(F)F |
Size | 25mg |
Supplier Page | http://www.selleckchem.com/products/cnx-2006.html |
Additional Information | https://file.selleck.cn/downloads/struct/CNX-2006-chemical-structure-s7206.gif |