Fedratinib hydrochloride hydrate

Fedratinib hydrochloride hydrate (TG-101348 hydrochloride hydrate, SAR 302503 hydrochloride hydrate) is a small-molecule, ATP-competitive inhibitor of JAK2 with IC50s of 3 nM for both JAK2 and JAK2V617F kinase. It induces cancer cell apoptosis and has potential for efficacious treatment of JAK2V617F-associated myeloproliferative disease.

Price Not Available 25mg Fedratinib hydrochloride hydrate Supplier Page

Trivial name	TG-101348 hydrochloride hydrate, SAR 302503 hydrochloride hydrate
Catalog Number	E5818
Molecular Formula	C26H39NO6S
CAS#	1374744-69-0
Inchi	InChI=1S/C26H39NO6S/c1-14-8-7-9-19-21(32-19)11-20(15(2)10-18-13-34-17(4)27-18)33-23(29)12-22(28)26(5,6)25(31)16(3)24(14)30/h10,13-14,16,19-22,24,28,30H,7-9,11-12H2,1-6H3/b15-10+/t14-,16+,19+,20-,21-,2 2-,24-/m0/s1
Inchi Key	HESCAJZNRMSMJG-KKQRBIROSA-N
SMILES	CC1CCCC2C(O2)CC(OC(=O)CC(C(C(=O)C(C1O)C)(C)C)O)C(=CC3=CSC(=N3)C)C
Size	25mg
Supplier Page	http://www.selleckchem.com/products/fedratinib-hydrochloride-hydrate.html
Additional Information	https://file.selleck.cn/downloads/struct/E5818-Fedratinib-hydrochloride-hydrate-chemical-structure.png