Rociletinib (CO-1686)

Rociletinib (CO-1686, AVL-301) is an irreversible, mutant-selective EGFR inhibitor with Ki of 21.5 nM and 303.3 nM for EGFRL858R/T790M and EGFRWT in cell-free assays, respectively. Phase 2.

Price Not Available 50mg Rociletinib (CO-1686) Supplier Page

Trivial name	AVL-301
Catalog Number	S7284
Molecular Formula	C27H28F3N7O3
CAS#	1374640-70-6
Inchi	InChI=1S/C27H28F3N7O3/c1-4-24(39)32-18-6-5-7-19(14-18)33-25-21(27(28,29)30)16-31-26(35-25)34-22-9-8-20(15-23(22)40-3)37-12-10-36(11-13-37)17(2)38/h4-9,14-16H,1,10-13H2,2-3H3,(H,32,39)(H2,31,33,34,35)
Inchi Key	HUFOZJXAKZVRNJ-UHFFFAOYSA-N
SMILES	CC(=O)N1CCN(CC1)C2=CC(=C(C=C2)NC3=NC=C(C(=N3)NC4=CC(=CC=C4)NC(=O)C=C)C(F)(F)F)OC
Size	50mg
Supplier Page	http://www.selleckchem.com/products/co-1686.html
Additional Information	https://file.selleck.cn/downloads/struct/CO-1686-chemical-structure-s7284.gif