(S)-crizotinib
(S)-crizotinib, the (S)-enantiomer of crizotinib, is a potent MTH1 (NUDT1) inhibitor with IC50 of 72 nM in a cell-free assay.
| Trivial name | N/A |
| Catalog Number | S7505 |
| Molecular Formula | C21H22Cl2FN5O |
| CAS# | 1374356-45-2 |
| Inchi | InChI=1S/C21H22Cl2FN5O/c1-12(19-16(22)2-3-17(24)20(19)23)30-18-8-13(9-27-21(18)25)14-10-28-29(11-14)15-4-6-26-7-5-15/h2-3,8-12,15,26H,4-7H2,1H3,(H2,25,27)/t12-/m0/s1 |
| Inchi Key | KTEIFNKAUNYNJU-LBPRGKRZSA-N |
| SMILES | CC(C1=C(C=CC(=C1Cl)F)Cl)OC2=C(N=CC(=C2)C3=CN(N=C3)C4CCNCC4)N |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/s-crizotinib.html |
| Additional Information | https://file.selleck.cn/downloads/struct/S-crizotinib-chemical-structure-s7505.gif |