GSK-J4 50mg
GSK J4 is a cell permeable prodrug rapidly hydrolyzed by macrophage esterases to GSK-J1, a potent selective jumonji H3K27 demethylase inhibitor; attenuates lipopolysaccharide (LPS)-induced proinflammatory cytokine production in primary human macrophages (IC50 = 9 uM for the inhibition of TNF?? release).
Trivial name | GSK-J4 50mg |
Catalog Number | A12732-50 |
Alternative Name(s) | ethyl 3-[[2-pyridin-2-yl-6-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)pyrimidin-4-yl]amino]propanoate |
Molecular Formula | C24H27N5O2 |
CAS# | 1373423-53-0 |
SMILES | N/A |
Size | 50mg |
Supplier Page | http://www.adooq.com/gsk-j4.html |