GSK J1
GSK-J1 is a highly potent inhibitor of H3K27 histone demethylase JMJD3 (KDM6B) and UTX (KDM6A) with IC50 of 60 nM in cell-free assays for JMJD3 (KDM6B) , respectively, >10-fold selectivity over other tested demethylases, with IC50 of 0.95μM and 1.76μM towards JARID1B/C.
| Trivial name | N/A |
| Catalog Number | S7581 |
| CAS# | 1373422-53-7 |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/gsk-j1.html |
| Additional Information | https://file.selleck.cn/downloads/struct/gsk-j1-chemical-structure-s7581.gif |