GSK2636771
GSK2636771 is a potent, orally bioavailable and selective inhibitor of PI3Kβ with >900-fold selectivity over PI3Kα/PI3Kγ and >10-fold over PI3Kδ. Sensitive to PTEN null cell lines.
Trivial name | N/A |
Catalog Number | S8002 |
Molecular Formula | C22H22F3N3O3 |
CAS# | 1372540-25-4 |
Inchi | InChI=1S/C22H22F3N3O3/c1-13-15(4-3-5-18(13)22(23,24)25)12-28-14(2)26-20-17(21(29)30)10-16(11-19(20)28)27-6-8-31-9-7-27/h3-5,10-11H,6-9,12H2,1-2H3,(H,29,30) |
Inchi Key | XTKLTGBKIDQGQL-UHFFFAOYSA-N |
SMILES | CC1=C(C=CC=C1C(F)(F)F)CN2C(=NC3=C(C=C(C=C32)N4CCOCC4)C(=O)O)C |
Size | 10mM/1mL |
Supplier Page | http://www.selleckchem.com/products/gsk2636771.html |
Additional Information | https://file.selleck.cn/downloads/struct/GSK2636771-chemical-structure-s8002.gif |