PRT062607 (P505-15) HCl
PRT062607 (P505-15, BIIB057, PRT-2607) HCl is a novel, highly selective Syk inhibitor with IC50 of 1 nM in cell-free assays, >80-fold selective for Syk than Fgr, PAK5, Lyn, FAK, Pyk2, FLT3, MLK1 and Zap70.
Trivial name | BIIB057, PRT-2607 |
Catalog Number | S8032 |
Molecular Formula | C19H23N9O.HCl |
CAS# | 1370261-97-4 |
Inchi | InChI=1S/C19H23N9O.ClH/c20-15-6-1-2-7-16(15)26-19-22-11-14(17(21)29)18(27-19)25-12-4-3-5-13(10-12)28-23-8-9-24-28;/h3-5,8-11,15-16H,1-2,6-7,20H2,(H2,21,29)(H2,22,25,26,27);1H/t15-,16+;/m0./s1 |
Inchi Key | RMNLLPXCNDZJMJ-IDVLALEDSA-N |
SMILES | C1CCC(C(C1)N)NC2=NC=C(C(=N2)NC3=CC(=CC=C3)N4N=CC=N4)C(=O)N.Cl |
Size | 1g |
Supplier Page | http://www.selleckchem.com/products/prt062607-p505-15-hcl.html |
Additional Information | https://file.selleck.cn/downloads/struct/P505-15-HCl-chemical-structure-s8032.gif |