PRT062607
PRT062607 is a highly specific, potent and orally bioavailable inhibitor of purified Spleen tyrosine kinase (SYK) with an IC50 of 1-2 nM. It exhibits significant anti-inflammatory activity and can be used in non-Hodgkin lymphoma (NHL), chronic lymphocytic leukemia (CLL) and rheumatoid arthritis research.
| Trivial name | P505-15, PRT-2607, BIIB-057 |
| Catalog Number | E7793 |
| Molecular Formula | C16H17FIN3O4 |
| CAS# | 1370261-96-3 |
| Inchi | InChI=1S/C16H17FIN3O4/c1-9-7-11(15(23)20-25-6-5-22)14(21(2)16(9)24)19-13-4-3-10(18)8-12(13)17/h3-4,7-8,19,22H,5-6H2,1-2H3,(H,20,23) |
| Inchi Key | RWEVIPRMPFNTLO-UHFFFAOYSA-N |
| SMILES | CC1=CC(=C(N(C1=O)C)NC2=C(C=C(C=C2)I)F)C(=O)NOCCO |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/prt062607.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E7793-PRT062607-chemical-structure.png |