Cerdulatinib (PRT062070) hydrochloride

Cerdulatinib (PRT-062070, PRT2070) hydrochloride is an oral active, multi-targeted tyrosine kinase inhibitor with IC50 of 12 nM/6 nM/8 nM/0.5 nM and 32 nM for JAK1/JAK2/JAK3/TYK2 and Syk, respectively. Also inhibits 19 other tested kinases with IC50 less than 200 nM.

Trivial name PRT2070 hydrochloride
Catalog Number S7634
Molecular Formula C20H28ClN7O3S
CAS# 1369761-01-2
Inchi InChI=1S/C20H27N7O3S.ClH/c1-2-31(29,30)27-11-9-26(10-12-27)16-7-5-15(6-8-16)24-20-22-13-17(18(21)28)19(25-20)23-14-3-4-14;/h5-8,13-14H,2-4,9-12H2,1H3,(H2,21,28)(H2,22,23,24,25);1H
Inchi Key IYULGYKOHUAYCG-UHFFFAOYSA-N
SMILES CCS(=O)(=O)N1CCN(CC1)C2=CC=C(C=C2)NC3=NC=C(C(=N3)NC4CC4)C(=O)N.Cl
Size 10mM/1mL
Supplier Page http://www.selleckchem.com/products/cerdulatinib-prt062070-prt2070.html
Additional Information https://file.selleck.cn/downloads/struct/cerdulatinib-prt-062070-chemical-structure-s7634.gif