KP-457
KP-457 (TNF-α-converting enzyme) is a selective inhibitor of ADAM17 with IC50 of 11.1 nM/L (cell-free assay). It also cleaves various molecules such as GPIbα, GPV, and TNF-α.
| Trivial name | TNF‐α‐converting enzyme |
| Catalog Number | E1386 |
| Molecular Formula | C21H24N2O7S2 |
| CAS# | 1365803-52-6 |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/kp-457.html |
| Additional Information | https://file.selleck.cn/downloads/struct/e1386-kp-457-chemical-structure.png |