LDC1267
LDC1267 is a highly selective TAM kinase inhibitor with IC50 of <5 nM, 8 nM, and 29 nM for Mer, Tyro3, and Axl, respectively. Displays lower activity against Met, Aurora B, Lck, Src, and CDK8.
| Trivial name | N/A |
| Catalog Number | S7638 |
| Molecular Formula | C30H26F2N4O5 |
| CAS# | 1361030-48-9 |
| Inchi | InChI=1S/C30H26F2N4O5/c1-5-40-28-16-36(23-8-6-18(31)12-17(23)2)35-29(28)30(37)34-19-7-9-25(21(32)13-19)41-24-10-11-33-22-15-27(39-4)26(38-3)14-20(22)24/h6-16H,5H2,1-4H3,(H,34,37) |
| Inchi Key | ISPBCAXOSOLFME-UHFFFAOYSA-N |
| SMILES | CCOC1=CN(N=C1C(=O)NC2=CC(=C(C=C2)OC3=C4C=C(C(=CC4=NC=C3)OC)OC)F)C5=C(C=C(C=C5)F)C |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/ldc1267.html |
| Additional Information | https://file.selleck.cn/downloads/struct/ldc1267-chemical-structure-s7638.gif |