Fidarestat
Fidarestat (SNK 860) is an inhibitor of aldose reductase, with IC50s of 26 nM, 33 μM, and 1.8 μM for aldose reductase, AKR1B10 and V301L AKR1B10, respectively; Fidarestat (SNK 860) has the potential to treat diabetic disease.
| Trivial name | SNK 860 |
| Catalog Number | E7937 |
| Molecular Formula | C23H26F2N2O4 |
| CAS# | 136087-85-9 |
| Inchi | InChI=1S/C23H26F2N2O4/c1-14(26-19(28)12-15-10-17(24)13-18(25)11-15)21(29)27-20(16-8-6-5-7-9-16)22(30)31-23(2,3)4/h5-11,13-14,20H,12H2,1-4H3,(H,26,28)(H,27,29)/t14-,20-/m0/s1 |
| Inchi Key | DWJXYEABWRJFSP-XOBRGWDASA-N |
| SMILES | CC(C(=O)NC(C1=CC=CC=C1)C(=O)OC(C)(C)C)NC(=O)CC2=CC(=CC(=C2)F)F |
| Size | 1mg |
| Supplier Page | http://www.selleckchem.com/products/fidarestat.html |
| Additional Information | https://file.selleck.cn/downloads/struct/e7937-fidarestat-chemical-structure-tube.png |