Lobetyolin is one of the important active ingredients extracted from the root of Codonopsis pilosula, which has a good protective effect on gastric mucosal damage. Lobetyolin can downregulate glutamine metabolism, contribute to drug-induced apoptosis and tumor growth inhibition, and lobetyolin significantly reduces the mRNA and protein expression of the amino acid transporter alanine-serine-cysteine ​​transporter 2 (ASCT2).