Necrosulfonamide

(E)-Necrosulfonamide is an inhibitor of necroptosis. Blocks mixed lineage kinase domain-like protein (MLKL), a critical substrate of receptor-interacting serine-threonine kinase 3 (RIP3) during necrosis. Prevents MLKL-RIP1-RIP3 necrosome complex from interacting with downstream necrosis effectors. Binds and inhibits gasdermin D. Inhibits pyroptosis.

Price Not Available 25 mg Necrosulfonamide Supplier Page

Catalog Number	T6904
Alternative Name(s)	(E)-Necrosulfonamide
Research Area	MAPK
Molecular Formula	C18H15N5O6S2
CAS#	1360614-48-7
Purity	99.17%
SMILES	COC1=C(NS(=O)(=O)C2=CC=C(NC(=O)\C=C\C3=CC=C(S3)[N+]([O-])=O)C=C2)N=CC=N1
Size	25 mg
Supplier Page	https://www.targetmol.com/compound/（E）-Necrosulfonamide
Additional Information	https://www.targetmol.com/datasheet/T6904