BRD-5529

BRD-5529 is a selective, cell-permeable CARD9-E3 ubiquitin ligase TRIM62 protein-protein interaction inhibitor (IC50 of 8.6 μM). BRD-5529 directly and selectively binds CARD9, disrupts TRIM62 recruitment, inhibits TRIM62-mediated ubiquitinylation and activation of CARD9, and demonstrates cellular activity and selectivity in CARD9-dependent pathways.

Price Not Available Inquiry BRD-5529 Supplier Page

Catalog Number	ABU-002
Alternative Name(s)	2-(4'-Carbamoyl-[1,4'-bipiperidin]-1'-yl)-5-(4-methylbenzamido)nicotinic acid
CAS#	1358488-78-4
Inchi	InChI=1S/C25H31N5O4/c1-17-5-7-18(8-6-17)22(31)28-19-15-20(23(32)33)21(27-16-19)29-13-9-25(10-14-29,24(26)34)30-11-3-2-4-12-30/h5-8,15-16H,2-4,9-14H2,1H3,(H2,26,34)(H,28,31)(H,32,33)
Inchi Key	ZXWHESBABUHJBE-UHFFFAOYSA-N
SMILES	O=C(O)C1=C(N2CCC(N3CCCCC3)(C(N)=O)CC2)N=CC(NC(C4=CC=C(C)C=C4)=O)=C1
Size	Inquiry
Supplier Page	https://www.agingclocks.com/brd-5529-item-1541.html