FL118
FL118(10,11-(Methylenedioxy)-20(S)-camptothecin), a Camptothecin analog, is a potent and orally active inhibitor of Survivin. FL118 also selectively and independently inhibits three additional cancer-associated survival genes Mcl-1, XIAP, and cIAP2 in a p53 status-independent manner. FL118 displays potent antitumor activity and can be used in cancer research.
| Trivial name | 10,11-(Methylenedioxy)-20(S)-camptothecin |
| Catalog Number | E1713 |
| Molecular Formula | C27H32N4O4S |
| CAS# | 135415-73-5 |
| SMILES | O=C(CSC1=NC2=CC=C(C=C2C(=O)N1CCC3=CC=CC=C3)N4CCOCC4)NCC5CCCO5 |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/fl118.html |
| Additional Information | https://file.selleck.cn/downloads/struct/e1713-FL118-chemical-structure.png |
