Poseltinib
Poseltinib (HM71224, LY3337641) shows a highly selective inhibition for Bruton’s tyrosine kinase (BTK) with IC50 of 1.95 nM, in which the selectivity toward other BMX, TEC and TXK are 0.3, 2.3 and 2.4 fold, respectively.
| Trivial name | HM71224, LY3337641 |
| Catalog Number | E2843 |
| Molecular Formula | C26H26N6O3 |
| CAS# | 1353552-97-2 |
| SMILES | CN1CCN(CC1)C2=CC=C(NC3=NC(=C4OC=CC4=N3)OC5=CC(=CC=C5)NC(=O)C=C)C=C2 |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/poseltinib.html |
| Additional Information | https://file.selleck.cn/downloads/struct/e2843-poseltinib-chemical-structure.gif |