CMS-121
CMS-121 is a quinolone derivative and an orally active acetyl-CoA carboxylase 1 (ACC1) inhibitor. CMS-121 protects HT22 cells against ischemia and oxidative damage with EC50 values of 7 nM and 200 nM, respectively. CMS-121 has strong neuroprotective, anti-inflammatory, antioxidative and renoprotective activities.
| Catalog Number | E7743 |
| Molecular Formula | C16H15F2N3O4S |
| CAS# | 1353224-53-9 |
| Inchi | InChI=1S/C16H15F2N3O4S/c1-23-13-5-6-19-12(14(13)24-2)8-26(22)16-20-10-4-3-9(25-15(17)18)7-11(10)21-16/h3-7,15H,8H2,1-2H3,(H,20,21) |
| Inchi Key | IQPSEEYGBUAQFF-UHFFFAOYSA-N |
| SMILES | COC1=C(C(=NC=C1)CS(=O)C2=NC3=C(N2)C=C(C=C3)OC(F)F)OC |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/cms-121.html |
| Additional Information | https://file.selleck.cn/downloads/struct/e7743-cms-121-chemical-structure-tube.png |