Voxtalisib (XL765) Analogue

Voxtalisib (SAR245409, XL765) Analogue is a dual inhibitor of mTOR/PI3K, mostly for p110γ with IC50 of 9 nM; also inhibits DNA-PK and mTOR. Phase 1/2.

Trivial name SAR245409
Catalog Number S1523
Molecular Formula C31H29N5O6S
CAS# 1349796-36-6
Inchi InChI=1S/C31H29N5O6S/c1-19-9-10-20(15-28(19)42-4)31(37)33-21-11-13-25(14-12-21)43(38,39)36-30-29(34-26-7-5-6-8-27(26)35-30)32-22-16-23(40-2)18-24(17-22)41-3/h5-18H,1-4H3,(H,32,34)(H,33,37)(H,35,36)
Inchi Key HJSSPYJVWLTYHG-UHFFFAOYSA-N
SMILES CC1=C(C=C(C=C1)C(=O)NC2=CC=C(C=C2)S(=O)(=O)NC3=NC4=CC=CC=C4N=C3NC5=CC(=CC(=C5)OC)OC)OC
Size 5mg
Supplier Page http://www.selleckchem.com/products/XL765(SAR245409).html
Additional Information https://file.selleck.cn/downloads/struct/XL765-chemical-structure-S1523.gif